Hello Bob,
Aspose.Pdf is fully compatible with .Net framework 3.5 and so far we haven’t found any issue with this version. We would also recommend you to upgrade to the latest version Aspose.Pdf 3.9.0.0 and in case you face any problem, please feel free to share.
You can also refer to following link for information regarding System Requirement, http://www.aspose.com/documentation/file-format-components/aspose.pdf-for-.net-and-java/system-requirements-for-net.html
Nayyer Shahbaz
Support Developer, Aspose Sialkot Team
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